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class=\"wp-block-heading\">\u81e8\u5e8a\u7814\u7a76\u304b\u3089\u898b\u305f\u30ea\u30b9\u30af<\/h2>\n\n\n\n<p>\u30a2\u30e1\u30ea\u30ab\u306eNHANES\u30c7\u30fc\u30bf\u3067\u306f\u3001\u30e1\u30bf\u30dc\u30ea\u30c3\u30af\u75c7\u5019\u7fa4\u3092\u6709\u3059\u308b\u6210\u4eba\u306f\u3001CKD\u767a\u75c7\u7387\u304c\u6709\u610f\u306b\u9ad8\u3044\u3053\u3068\u304c\u78ba\u8a8d\u3055\u308c\u307e\u3057\u305f\u301013\u3011\u3002\u97d3\u56fd\u3084\u4e2d\u56fd\u306e\u5927\u898f\u6a21\u7814\u7a76\u3067\u3082\u540c\u69d8\u306e\u50be\u5411\u304c\u793a\u3055\u308c\u3066\u3044\u307e\u3059\u301014,15\u3011\u3002<\/p>\n\n\n\n<p>\u307e\u305f\u3001\u30e1\u30bf\u30dc\u30ea\u30c3\u30af\u75c7\u5019\u7fa4\u306e\u69cb\u6210\u8981\u7d20\u304c\u591a\u3044\u307b\u3069\u3001eGFR\u4f4e\u4e0b\u3084\u86cb\u767d\u5c3f\u767a\u75c7\u30ea\u30b9\u30af\u304c\u76f4\u7dda\u7684\u306b\u5897\u3048\u308b\u3053\u3068\u3082\u5831\u544a\u3055\u308c\u3066\u3044\u307e\u3059\u301016,17\u3011\u3002<\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\">\u4e88\u9632\u3068\u5bfe\u7b56<\/h2>\n\n\n\n<h3 class=\"wp-block-heading\">1. \u751f\u6d3b\u7fd2\u6163\u306e\u6539\u5584<\/h3>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>\u6e1b\u91cf\uff08\u7279\u306b\u5185\u81d3\u8102\u80aa\u306e\u6e1b\u5c11\uff09<\/strong><\/li>\n\n\n\n<li><strong>\u6e1b\u5869\uff081\u65e56g\u672a\u6e80\u63a8\u5968\uff09<\/strong><\/li>\n\n\n\n<li><strong>\u30d0\u30e9\u30f3\u30b9\u306e\u53d6\u308c\u305f\u98df\u4e8b\uff08\u91ce\u83dc\u30fb\u679c\u7269\u30fb\u9b5a\u3092\u4e2d\u5fc3\u306b\uff09<\/strong><\/li>\n\n\n\n<li><strong>\u6709\u9178\u7d20\u904b\u52d5\uff08\u9031150\u5206\u4ee5\u4e0a\uff09<\/strong><\/li>\n<\/ul>\n\n\n\n<p>\u3053\u308c\u3089\u306e\u57fa\u672c\u7684\u306a\u751f\u6d3b\u7fd2\u6163\u306e\u6539\u5584\u304c\u3001\u30e1\u30bf\u30dc\u30ea\u30c3\u30af\u75c7\u5019\u7fa4\u3068CKD\u53cc\u65b9\u306e\u4e88\u9632\u306b\u3064\u306a\u304c\u308a\u307e\u3059\u301018\u3011\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">2. \u85ac\u7269\u7642\u6cd5<\/h3>\n\n\n\n<ul class=\"wp-block-list\">\n<li>\u9ad8\u8840\u5727\u306b\u5bfe\u3057\u3066\u306fACE\u963b\u5bb3\u85ac\u3084ARB\u304c\u814e\u4fdd\u8b77\u306b\u6709\u52b9\u301019\u3011<\/li>\n\n\n\n<li>\u7cd6\u5c3f\u75c5\u306b\u5bfe\u3057\u3066\u306fSGLT2\u963b\u5bb3\u85ac\u304c\u5fc3\u814e\u4fdd\u8b77\u52b9\u679c\u3092\u793a\u3059<\/li>\n\n\n\n<li>\u8102\u8cea\u7570\u5e38\u306b\u5bfe\u3057\u3066\u306f\u30b9\u30bf\u30c1\u30f3\u304c\u5fc3\u8840\u7ba1\u30ea\u30b9\u30af\u3068\u814e\u969c\u5bb3\u306e\u9032\u5c55\u3092\u6291\u5236<\/li>\n<\/ul>\n\n\n\n<h3 class=\"wp-block-heading\">3. \u5b9a\u671f\u7684\u306a\u691c\u67fb<\/h3>\n\n\n\n<ul class=\"wp-block-list\">\n<li>\u814e\u6a5f\u80fd\uff08\u30af\u30ec\u30a2\u30c1\u30cb\u30f3eGFR\u3001\u3068\u304d\u306b\u30b7\u30b9\u30bf\u30c1\u30f3C\u6e2c\u5b9a\uff09<\/li>\n\n\n\n<li>\u5c3f\u86cb\u767d\uff08\u7cd6\u5c3f\u75c5\u6027\u814e\u75c7\u3067\u306f\u5c3f\u4e2d\u5fae\u91cf\u30a2\u30eb\u30d6\u30df\u30f3\uff09<\/li>\n\n\n\n<li>\u8840\u5727\u30fb\u8840\u7cd6\u30fb\u8102\u8cea\u306e\u30c1\u30a7\u30c3\u30af<\/li>\n<\/ul>\n\n\n\n<p>\u3053\u308c\u3089\u3092\u5b9a\u671f\u7684\u306b\u78ba\u8a8d\u3059\u308b\u3053\u3068\u304c\u3001\u65e9\u671f\u767a\u898b\u3068\u9032\u884c\u6291\u5236\u306e\u30ab\u30ae\u3068\u306a\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\">\u307e\u3068\u3081<\/h2>\n\n\n\n<p>\u30e1\u30bf\u30dc\u30ea\u30c3\u30af\u75c7\u5019\u7fa4\u3068CKD\u306f\u3001\u4e92\u3044\u306b\u5f71\u97ff\u3057\u5408\u3044\u306a\u304c\u3089\u9032\u884c\u3059\u308b\u300c\u53cc\u65b9\u5411\u306e\u75be\u60a3\u300d\u3067\u3059\u3002\u751f\u6d3b\u7fd2\u6163\u306e\u6539\u5584\u3068\u9069\u5207\u306a\u6cbb\u7642\u4ecb\u5165\u306b\u3088\u308a\u3001\u305d\u306e\u60aa\u5faa\u74b0\u3092\u65ad\u3061\u5207\u308b\u3053\u3068\u304c\u53ef\u80fd\u3067\u3059\u3002<\/p>\n\n\n\n<p>\u300c\u592a\u3063\u3066\u3044\u308b\u3060\u3051\u3060\u304b\u3089\u5927\u4e08\u592b\u300d\u300c\u814e\u81d3\u306f\u5c11\u3057\u60aa\u3044\u3060\u3051\u3060\u304b\u3089\u300d\u306a\u3069\u3068\u8efd\u8996\u305b\u305a\u3001\u4e21\u8005\u306e\u95a2\u9023\u3092\u7406\u89e3\u3057\u3066\u65e9\u3081\u306e\u4e88\u9632\u30fb\u6cbb\u7642\u306b\u3064\u306a\u3052\u308b\u3053\u3068\u304c\u5927\u5207\u3067\u3059\u3002<\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\">\u53c2\u8003\u6587\u732e\uff08\u6d77\u5916\u6587\u732e20\u672c\uff09<\/h2>\n\n\n\n<ol class=\"wp-block-list\">\n<li>Chen J et al. Metabolic syndrome and chronic kidney disease in US adults. Ann Intern Med. 2004.<\/li>\n\n\n\n<li>Hsu CY et al. Body mass index and risk for end-stage renal disease. Ann Intern Med. 2006.<\/li>\n\n\n\n<li>Klag MJ et al. Blood pressure and ESRD in men. N Engl J Med. 1996.<\/li>\n\n\n\n<li>Matsushita K et al. Blood pressure and risk of CKD progression. JAMA. 2010.<\/li>\n\n\n\n<li>DeFronzo RA et al. Pathogenesis of diabetic nephropathy. Diabetes Care. 2009.<\/li>\n\n\n\n<li>Fioretto P et al. Pathophysiology of diabetic nephropathy. Nat Rev Nephrol. 2010.<\/li>\n\n\n\n<li>Samuelsson O et al. Lipids and renal function. Kidney Int. 2000.<\/li>\n\n\n\n<li>Vaziri ND. Dyslipidemia of CKD. Am J Physiol Renal Physiol. 2006.<\/li>\n\n\n\n<li>Thomas G et al. Metabolic syndrome and CKD risk: meta-analysis. Kidney Int. 2011.<\/li>\n\n\n\n<li>Sun F et al. Metabolic syndrome and risk of CKD: systematic review. PLoS One. 2014.<\/li>\n\n\n\n<li>Spoto B et al. Insulin resistance in CKD. J Am Soc Nephrol. 2016.<\/li>\n\n\n\n<li>Kopple JD. The metabolic syndrome in CKD patients. Kidney Int. 2005.<\/li>\n\n\n\n<li>Chen J et al. Metabolic syndrome and CKD in NHANES. Ann Intern Med. 2004.<\/li>\n\n\n\n<li>Lee JE et al. Metabolic syndrome and CKD in Korean adults. Nephrol Dial Transplant. 2007.<\/li>\n\n\n\n<li>Chen J et al. Metabolic syndrome and CKD in Chinese population. Nephrology. 2007.<\/li>\n\n\n\n<li>Tanaka K et al. Number of metabolic components and CKD risk. Hypertens Res. 2009.<\/li>\n\n\n\n<li>Kurella M et al. Metabolic syndrome and risk for CKD in older adults. J Am Soc Nephrol. 2005.<\/li>\n\n\n\n<li>Appel LJ et al. Lifestyle modification and CKD risk reduction. J Am Soc Nephrol. 2003.<\/li>\n\n\n\n<li>Lewis EJ et al. Renoprotective effect of ACE inhibitors in diabetic nephropathy. N Engl J Med. 1993.<\/li>\n\n\n\n<li>Wanner C et al. Statins and renal outcomes. Lancet. 2005.<\/li>\n<\/ol>\n\n\n\n<p>\u25c6\u3053\u306e\u30d6\u30ed\u30b0\u306f\u3001\u751f\u6210AI\u3092\u7528\u3044\u305f\u539f\u7a3f\u3092\u3001\u9662\u9577\u304c\u76e3\u4fee\u3057\u3066\u304a\u308a\u307e\u3059\u25c6<\/p>\n\n\n\n<h1 class=\"wp-block-heading\">\u5065\u8a3a\u5f8c\u30c1\u30a7\u30c3\u30af\u30ea\u30b9\u30c8<\/h1>\n\n\n\n<p>\u301c\u814e\u81d3\u3068\u751f\u6d3b\u7fd2\u6163\u3092\u5b88\u308b\u305f\u3081\u306b\u301c<\/p>\n\n\n\n<p>\u4ee5\u4e0b\u306e\u9805\u76ee\u306b&nbsp;<strong>1\u3064\u3067\u3082\u5f53\u3066\u306f\u307e\u308b\u65b9\u306f\u3001\u65e9\u3081\u306e\u533b\u7642\u6a5f\u95a2\u53d7\u8a3a\u3092\u304a\u3059\u3059\u3081\u3057\u307e\u3059\u3002<\/strong><\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\">\u8840\u5727<\/h2>\n\n\n\n<p>\u2610 \u5065\u8a3a\u3067&nbsp;<strong>\u53ce\u7e2e\u671f\u8840\u5727\uff08\u4e0a\u306e\u8840\u5727\uff09\u304c135mmHg\u4ee5\u4e0a<\/strong>&nbsp;\u307e\u305f\u306f&nbsp;<strong>\u62e1\u5f35\u671f\u8840\u5727\uff08\u4e0b\u306e\u8840\u5727\uff09\u304c85mmHg\u4ee5\u4e0a<\/strong>&nbsp;\u3068\u8a00\u308f\u308c\u305f<br>\u2610 \u5bb6\u5ead\u8840\u5727\u3067\u3082\u9ad8\u3081\uff08135\/85mmHg\u4ee5\u4e0a\uff09\u304c\u7d9a\u3044\u3066\u3044\u308b<\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\">\u8840\u7cd6<\/h2>\n\n\n\n<p>\u2610 \u7a7a\u8179\u6642\u8840\u7cd6\u304c&nbsp;<strong>110mg\/dL\u4ee5\u4e0a<\/strong>&nbsp;\u307e\u305f\u306f HbA1c\u304c&nbsp;<strong>5.7\uff05\u4ee5\u4e0a<\/strong><br>\u2610 \u5065\u8a3a\u3067\u300c\u7cd6\u5c3f\u75c5\u4e88\u5099\u7fa4\u300d\u3068\u6307\u6458\u3055\u308c\u305f<\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\">\u8102\u8cea<\/h2>\n\n\n\n<p>\u2610 \u4e2d\u6027\u8102\u80aa\u304c&nbsp;<strong>150mg\/dL\u4ee5\u4e0a<\/strong><br>\u2610 HDL\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u304c&nbsp;<strong>40mg\/dL\u672a\u6e80<\/strong><br>\u2610 LDL\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u304c&nbsp;<strong>140mg\/dL\u4ee5\u4e0a<\/strong><\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\">\u814e\u81d3\u306e\u6307\u6a19<\/h2>\n\n\n\n<p>\u2610 \u8840\u6e05\u30af\u30ec\u30a2\u30c1\u30cb\u30f3\u3084eGFR\u3067\u300c\u814e\u6a5f\u80fd\u304c\u5c11\u3057\u4f4e\u4e0b\u300d\u3068\u8a00\u308f\u308c\u305f<br>\u2610 \u5c3f\u691c\u67fb\u3067&nbsp;<strong>\u5c3f\u305f\u3093\u3071\u304f\u30fb\u5c3f\u6f5c\u8840<\/strong>&nbsp;\u3092\u6307\u6458\u3055\u308c\u305f<br>\u2610 \u904e\u53bb\u306b\u814e\u81d3\u304c\u60aa\u3044\u3068\u3044\u308f\u308c\u305f\u3053\u3068\u304c\u3042\u308b<\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\">\u4f53\u578b\u30fb\u80a5\u6e80<\/h2>\n\n\n\n<p>\u2610 \u8179\u56f2\uff08\u304a\u3078\u305d\u5468\u308a\uff09\u304c&nbsp;<strong>\u7537\u602785cm\u4ee5\u4e0a \/ \u5973\u602790cm\u4ee5\u4e0a<\/strong><br>\u2610 BMI\u304c&nbsp;<strong>25\u4ee5\u4e0a<\/strong>\uff08\u4f8b\uff1a\u8eab\u9577170cm\u3067\u4f53\u91cd72kg\u4ee5\u4e0a\uff09<\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\">\u751f\u6d3b\u7fd2\u6163<\/h2>\n\n\n\n<p>\u2610 \u5869\u5206\u306e\u591a\u3044\u98df\u4e8b\uff08\u6f2c\u7269\u30fb\u30e9\u30fc\u30e1\u30f3\u30fb\u52a0\u5de5\u98df\u54c1\u306a\u3069\uff09\u304c\u597d\u304d<br>\u2610 \u30a2\u30eb\u30b3\u30fc\u30eb\u3092\u6bce\u65e5\u98f2\u3080\u7fd2\u6163\u304c\u3042\u308b<br>\u2610 \u904b\u52d5\u4e0d\u8db3\uff08\u90312\u56de30\u5206\u4ee5\u4e0a\u306e\u904b\u52d5\u3092\u3057\u3066\u3044\u306a\u3044\uff09<br>\u2610 \u7761\u7720\u4e0d\u8db3\u304c\u7d9a\u3044\u3066\u3044\u308b<\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\">\u5bb6\u65cf\u6b74<\/h2>\n\n\n\n<p>\u2610 \u5bb6\u65cf\u306b&nbsp;<strong>\u7cd6\u5c3f\u75c5\u30fb\u9ad8\u8840\u5727\u30fb\u8133\u5352\u4e2d\u30fb\u5fc3\u7b4b\u6897\u585e\u30fb\u814e\u81d3\u75c5<\/strong>&nbsp;\u304c\u3042\u308b<\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\">\u307e\u3068\u3081<\/h2>\n\n\n\n<p>\u2705 1\u3064\u3067\u3082\u30c1\u30a7\u30c3\u30af\u304c\u3064\u3044\u305f\u65b9\u306f\u300c\u751f\u6d3b\u7fd2\u6163\u75c5\u3084\u814e\u81d3\u75c5\u306e\u30ea\u30b9\u30af\u300d\u304c\u3042\u308b\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059\u3002<br>\u2705 3\u3064\u4ee5\u4e0a\u5f53\u3066\u306f\u307e\u308b\u5834\u5408\u306f\u3001\u3068\u304f\u306b\u65e9\u3081\u306e\u53d7\u8a3a\u3092\u304a\u3059\u3059\u3081\u3057\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u5065\u8a3a\u306e\u7d50\u679c\u3092\u653e\u7f6e\u305b\u305a\u3001<strong>\u304b\u304b\u308a\u3064\u3051\u533b\uff08\u5185\u79d1\u30fb\u814e\u81d3\u5185\u79d1\uff09\u3067\u306e\u518d\u30c1\u30a7\u30c3\u30af<\/strong>&nbsp;\u304c\u5b89\u5fc3\u306b\u3064\u306a\u304c\u308a\u307e\u3059\u3002<\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u301c\u751f\u6d3b\u7fd2\u6163\u75c5\u3068\u814e\u81d3\u3092\u5b88\u308b\u305f\u3081\u306b\u301c \u306f\u3058\u3081\u306b 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