{"id":223,"date":"2025-12-04T21:45:32","date_gmt":"2025-12-04T12:45:32","guid":{"rendered":"https:\/\/miyamotojinnaika.jp\/blog\/?p=223"},"modified":"2025-12-04T21:45:34","modified_gmt":"2025-12-04T12:45:34","slug":"post-223","status":"publish","type":"post","link":"https:\/\/miyamotojinnaika.jp\/blog\/post-223\/","title":{"rendered":"12\u67082\u65e5\uff08\u706b\uff09\u3088\u308a\u300c\u8840\u4e2d\u30a6\u30ed\u30e2\u30b8\u30e5\u30ea\u30f3\u6e2c\u5b9a\u300d\u3092\u5c0e\u5165\u3057\u307e\u3057\u305f"},"content":{"rendered":"\n<h2 class=\"wp-block-heading\">\u2015 CKD\u60a3\u8005\u3055\u3093\u3060\u3051\u3067\u306a\u304f\u3001\u5065\u5eb7\u7ba1\u7406\u3092\u91cd\u8996\u3059\u308b\u3059\u3079\u3066\u306e\u65b9\u306b \u2015<\/h2>\n\n\n\n<p>\u814e\u81d3\u5c02\u9580\u30af\u30ea\u30cb\u30c3\u30af\u3068\u3057\u3066\u3001\u5f53\u9662\u3067\u306f\u3053\u308c\u307e\u3067\u3082\u30af\u30ec\u30a2\u30c1\u30cb\u30f3\u3001\u30b7\u30b9\u30bf\u30c1\u30f3C\u3001\u5c3f\u691c\u67fb\u3001\u814e\u30a8\u30b3\u30fc\u306a\u3069\u591a\u89d2\u7684\u306a\u814e\u8a55\u4fa1\u3092\u884c\u3063\u3066\u304d\u307e\u3057\u305f\u3002\u3057\u304b\u3057\u3001\u8fd1\u5e74\u306e\u7814\u7a76\u304c\u660e\u3089\u304b\u306b\u3057\u305f\u4e8b\u5b9f\u3068\u3057\u3066\u3001<strong>\u814e\u81d3\u306e\u5065\u5eb7\u306f\u7cf8\u7403\u4f53\u3060\u3051\u3067\u306f\u8a9e\u308c\u305a\u3001\u300c\u5c3f\u7d30\u7ba1\u300d\u306e\u6a5f\u80fd\u3092\u3069\u3046\u8a55\u4fa1\u3059\u308b\u304b\u304c\u4e0d\u53ef\u6b20<\/strong>\u306b\u306a\u3063\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u3053\u3046\u3057\u305f\u77e5\u898b\u3092\u8e0f\u307e\u3048\u3001\u5f53\u9662\u3067\u306f&nbsp;<strong>2025\u5e7412\u67082\u65e5\uff08\u706b\uff09\u3088\u308a\u3001\u30ec\u30ce\u30d7\u30ed\u30c6\u30af\u30c8\u793e\u304c\u63d0\u4f9b\u3059\u308b\u300c\u8840\u4e2d\u30a6\u30ed\u30e2\u30b8\u30e5\u30ea\u30f3\u6e2c\u5b9a\u300d\u3092\u6b63\u5f0f\u306b\u5c0e\u5165<\/strong>\u3057\u307e\u3057\u305f\u3002<br>\u3053\u306e\u691c\u67fb\u306f\u3001\u3059\u3067\u306b CKD\uff08\u6162\u6027\u814e\u81d3\u75c5\uff09\u3067\u901a\u9662\u4e2d\u306e\u65b9\u3060\u3051\u3067\u306a\u304f\u3001<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>\u5065\u8a3a\u3067\u814e\u6a5f\u80fd\u306e\u4f4e\u4e0b\u3092\u6307\u6458\u3055\u308c\u305f\u65b9<\/li>\n\n\n\n<li>\u7cd6\u5c3f\u75c5\u30fb\u9ad8\u8840\u5727\u30fb\u8102\u8cea\u7570\u5e38\u75c7\u306a\u3069\u751f\u6d3b\u7fd2\u6163\u75c5\u304c\u3042\u308b\u65b9<\/li>\n\n\n\n<li>\u5bb6\u65cf\u306b\u814e\u81d3\u75c5\u306e\u65b9\u304c\u3044\u308b\u305f\u3081\u5c06\u6765\u304c\u4e0d\u5b89\u306a\u65b9<\/li>\n\n\n\n<li>\u598a\u5a20\u3092\u5e0c\u671b\u3055\u308c\u308b\u5973\u6027<\/li>\n\n\n\n<li>\u904e\u53bb\u306b\u6025\u6027\u814e\u969c\u5bb3\uff08AKI\uff09\u3092\u7d4c\u9a13\u3057\u305f\u65b9<\/li>\n\n\n\n<li>\u5065\u5eb7\u5bff\u547d\u3092\u5ef6\u3070\u3057\u305f\u3044\u65b9<\/li>\n<\/ul>\n\n\n\n<p>\u306a\u3069\u3001\u5e45\u5e83\u3044\u65b9\u306b\u5927\u304d\u306a\u4fa1\u5024\u304c\u3042\u308b\u691c\u67fb\u3067\u3059\u3002<\/p>\n\n\n\n<p>\u672c\u8a18\u4e8b\u3067\u306f\u3001\u814e\u81d3\u306e\u57fa\u790e\u304b\u3089\u3001\u8840\u4e2d\u30a6\u30ed\u30e2\u30b8\u30e5\u30ea\u30f3\u304c\u306a\u305c\u91cd\u8981\u306a\u306e\u304b\u3001\u3069\u306e\u3088\u3046\u306a\u672a\u6765\u4e88\u6e2c\u304c\u53ef\u80fd\u306b\u306a\u308b\u306e\u304b\u307e\u3067\u3001\u7db2\u7f85\u7684\u306b\u89e3\u8aac\u3057\u307e\u3059\u3002<\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h1 class=\"wp-block-heading\">\u25a0 1. \u814e\u81d3\u75c5\u304c\u5897\u3048\u7d9a\u3051\u308b\u65e5\u672c\u3067\u5fc5\u8981\u3068\u3055\u308c\u308b\u300c\u65b0\u3057\u3044\u814e\u8a55\u4fa1\u300d<\/h1>\n\n\n\n<p>\u65e5\u672c\u306eCKD\u60a3\u8005\u306f&nbsp;<strong>\u7d041,330\u4e07\u4eba<\/strong>&nbsp;\u3068\u63a8\u5b9a\u3055\u308c\u3001\u8d85\u9ad8\u9f62\u793e\u4f1a\u3092\u80cc\u666f\u306b\u3055\u3089\u306b\u5897\u52a0\u50be\u5411\u306b\u3042\u308a\u307e\u3059\u3002<br>\u3057\u304b\u3057\u591a\u304f\u306e\u65b9\u306f\u3001\u814e\u81d3\u304c\u60aa\u304f\u306a\u308b\u307e\u3067&nbsp;<strong>\u307b\u3068\u3093\u3069\u81ea\u899a\u75c7\u72b6\u304c\u3042\u308a\u307e\u305b\u3093<\/strong>\u3002<\/p>\n\n\n\n<p>\u73fe\u5728\u306e\u4fdd\u967a\u8a3a\u7642\u3067\u884c\u308f\u308c\u308b\u814e\u6a5f\u80fd\u691c\u67fb\u306e\u591a\u304f\u306f\u3001<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>\u30af\u30ec\u30a2\u30c1\u30cb\u30f3\uff08eGFR\uff09<\/li>\n\n\n\n<li>\u5c3f\u305f\u3093\u3071\u304f<\/li>\n\n\n\n<li>\u5c3f\u30a2\u30eb\u30d6\u30df\u30f3<\/li>\n<\/ul>\n\n\n\n<p>\u306a\u3069\u3001<strong>\u7cf8\u7403\u4f53\uff08\u308d\u904e\u88c5\u7f6e\uff09<\/strong>&nbsp;\u306e\u72b6\u614b\u3092\u4e2d\u5fc3\u306b\u5224\u65ad\u3059\u308b\u4ed5\u7d44\u307f\u306b\u306a\u3063\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u3057\u304b\u3057\u814e\u81d3\u306f\u7cf8\u7403\u4f53\u3060\u3051\u3067\u306f\u306a\u304f\u3001<br><strong>\u8840\u6d41\u8abf\u6574\u30fb\u8001\u5ec3\u7269\u306e\u518d\u5438\u53ce\u30fb\u5869\u5206\u8abf\u6574\u30fb\u30db\u30eb\u30e2\u30f3\u7523\u751f<\/strong>\u306a\u3069\u3092\u62c5\u3046\u300c\u5c3f\u7d30\u7ba1\u300d\u304c\u5168\u4f53\u306e\u5927\u90e8\u5206\u3092\u5360\u3081\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u8fd1\u5e74\u3001\u814e\u81d3\u5b66\u3067\u306f\u6b21\u306e\u3088\u3046\u306a\u6982\u5ff5\u304c\u6ce8\u76ee\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h1 class=\"wp-block-heading\">\u25a0 2. \u300c\u814e\u4e88\u5099\u529b\uff08renal reserve\uff09\u300d\u3068\u3044\u3046\u8003\u3048\u65b9<\/h1>\n\n\n\n<p>\u814e\u81d3\u306b\u306f\u3001\u666e\u6bb5\u4f7f\u308f\u308c\u3066\u3044\u306a\u3044\u201c\u4f59\u529b\u201d\uff1d<strong>\u814e\u4e88\u5099\u529b<\/strong>\u304c\u3042\u308a\u3001<br>\u3053\u308c\u304c\u8c4a\u5bcc\u306a\u4eba\u307b\u3069\u3001\u814e\u81d3\u306e\u30b9\u30c8\u30ec\u30b9\u304b\u3089\u56de\u5fa9\u3057\u3084\u3059\u3044\u3068\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u3057\u304b\u3057\u3001\u5f93\u6765\u306e\u691c\u67fb\u3067\u306f\u3053\u306e\u814e\u4e88\u5099\u529b\u3092\u6349\u3048\u308b\u3053\u3068\u304c\u96e3\u3057\u304f\u3001<br>\u814e\u81d3\u304c\u60aa\u5316\u3057\u3066\u521d\u3081\u3066\u7570\u5e38\u304c\u8868\u308c\u308b\u3053\u3068\u3082\u591a\u3044\u306e\u304c\u73fe\u72b6\u3067\u3059\u3002<\/p>\n\n\n\n<p>\u305d\u3053\u3067\u6ce8\u76ee\u3055\u308c\u3066\u3044\u308b\u306e\u304c&nbsp;<strong>\u8840\u4e2d\u30a6\u30ed\u30e2\u30b8\u30e5\u30ea\u30f3<\/strong>\u3067\u3059\u3002<\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h1 class=\"wp-block-heading\">\u25a0 3. \u8840\u4e2d\u30a6\u30ed\u30e2\u30b8\u30e5\u30ea\u30f3\u3068\u306f\uff1f<\/h1>\n\n\n\n<p>\u30a6\u30ed\u30e2\u30b8\u30e5\u30ea\u30f3\uff08Uromodulin\uff09\u306f\u3001\u814e\u81d3\u306e\u4e2d\u3067\u3082<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>\u30d8\u30f3\u30ec\u4fc2\u8e44\u4e0a\u884c\u811a\uff08Thick ascending limb\uff09<\/strong><\/li>\n\n\n\n<li><strong>\u9060\u4f4d\u5c3f\u7d30\u7ba1\u306e\u4e00\u90e8<\/strong><\/li>\n<\/ul>\n\n\n\n<p>\u3067\u306e\u307f\u7523\u751f\u3055\u308c\u308b\u3001\u4e16\u754c\u3067\u3082\u5e0c\u5c11\u306a\u201c\u814e\u81d3\u7279\u7570\u7684\u30bf\u30f3\u30d1\u30af\u8cea\u201d\u3067\u3059\u3002<\/p>\n\n\n\n<p>\u30ec\u30ce\u30d7\u30ed\u30c6\u30af\u30c8\u793e\u306f\u6b21\u306e\u3088\u3046\u306b\u8aac\u660e\u3057\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<blockquote class=\"wp-block-quote is-layout-flow wp-block-quote-is-layout-flow\">\n<p><strong>\u300c\u30a6\u30ed\u30e2\u30b8\u30e5\u30ea\u30f3\u306f\u3001\u814e\u81d3\u3067\u3057\u304b\u4f5c\u3089\u308c\u306a\u3044\u3001\u304d\u308f\u3081\u3066\u81d3\u5668\u7279\u7570\u6027\u306e\u9ad8\u3044\u86cb\u767d\u8cea\u3067\u3059\u3002\u3057\u304b\u3082\u3001\u814e\u81d3\u306e\u4e2d\u3067\u3082\u300e\u5c3f\u7d30\u7ba1\u300f\u3068\u547c\u3070\u308c\u308b\u9650\u3089\u308c\u305f\u90e8\u4f4d\u3067\u306e\u307f\u7523\u751f\u3055\u308c\u307e\u3059\u3002\u300d<\/strong><\/p>\n<\/blockquote>\n\n\n\n<p>\u3055\u3089\u306b\u3001<\/p>\n\n\n\n<blockquote class=\"wp-block-quote is-layout-flow wp-block-quote-is-layout-flow\">\n<p><strong>\u300c\u8840\u4e2d\u30a6\u30ed\u30e2\u30b8\u30e5\u30ea\u30f3\u6fc3\u5ea6\u306f\u3001\u814e\u81d3\u306e\u50cd\u304d\u3092\u30c0\u30a4\u30ec\u30af\u30c8\u306b\u53cd\u6620\u3057\u3066\u304a\u308a\u3001\u5f93\u6765\u306e\u30af\u30ec\u30a2\u30c1\u30cb\u30f3\u3084\u30b7\u30b9\u30bf\u30c1\u30f3C\u3068\u3044\u3063\u305f\u9593\u63a5\u7684\u306a\u30de\u30fc\u30ab\u30fc\u3067\u306f\u6349\u3048\u304d\u308c\u306a\u304b\u3063\u305f\u300e\u814e\u81d3\u306e\u58f0\u300f\u3092\u3001\u3088\u308a\u76f4\u63a5\u7684\u306b\u201c\u8074\u304f\u201d\u3053\u3068\u304c\u53ef\u80fd\u306b\u306a\u308a\u307e\u3059\u3002\u300d<\/strong><\/p>\n<\/blockquote>\n\n\n\n<p>\u3068\u8a18\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u3064\u307e\u308a\u8840\u4e2d\u30a6\u30ed\u30e2\u30b8\u30e5\u30ea\u30f3\u306f<br><strong>\u201c\u814e\u81d3\u81ea\u8eab\u306e\u5143\u6c17\u5ea6\u30fb\u56de\u5fa9\u529b\u3092\u6620\u3057\u51fa\u3059\u30b7\u30b0\u30ca\u30eb\u201d<\/strong>&nbsp;\u3068\u8a00\u3048\u307e\u3059\u3002<\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h1 class=\"wp-block-heading\">\u25a0 4. \u8840\u4e2d\u30a6\u30ed\u30e2\u30b8\u30e5\u30ea\u30f3\u306e\u6570\u5024\u304c\u793a\u3059\u610f\u5473<\/h1>\n\n\n\n<p>\u30ec\u30ce\u30d7\u30ed\u30c6\u30af\u30c8\u793e\u304c\u793a\u3059\u53c2\u8003\u5024\u306f\u4ee5\u4e0b\u306e\u901a\u308a\u3067\u3059\u3002<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>200\u301c400 ng\/mL\uff1a\u814e\u6a5f\u80fd\u304c\u6982\u306d\u4fdd\u305f\u308c\u3066\u3044\u308b<\/strong><\/li>\n\n\n\n<li><strong>150 ng\/mL \u672a\u6e80\uff1aCKD\uff08eGFR &lt; 60\uff09\u3092\u793a\u5506<\/strong><\/li>\n\n\n\n<li><strong>30\u301c40 ng\/mL \u672a\u6e80\uff1a\u672b\u671f\u814e\u4e0d\u5168\uff08eGFR &lt; 15\uff09\u3092\u793a\u5506<\/strong><\/li>\n<\/ul>\n\n\n\n<p>\u3053\u308c\u306f\u3059\u306a\u308f\u3061\u3001\u30a6\u30ed\u30e2\u30b8\u30e5\u30ea\u30f3\u306f\u814e\u81d3\u306e\u30c0\u30e1\u30fc\u30b8\u3092&nbsp;<strong>\u65e9\u671f\u304b\u3089\u53cd\u6620\u3059\u308b<\/strong>&nbsp;\u3060\u3051\u3067\u306a\u304f\u3001<strong>\u91cd\u75c7\u5ea6\u3068\u76f4\u7dda\u7684\u306b\u76f8\u95a2\u3059\u308b<\/strong>&nbsp;\u3068\u3044\u3046\u7279\u5fb4\u3092\u6301\u3064\u3053\u3068\u3092\u610f\u5473\u3057\u307e\u3059\u3002<\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h1 class=\"wp-block-heading\">\u25a0 5. \u8840\u4e2d\u30a6\u30ed\u30e2\u30b8\u30e5\u30ea\u30f3\u304c\u512a\u308c\u3066\u3044\u308b\u7406\u7531<\/h1>\n\n\n\n<p>\u4ee5\u4e0b\u306f\u6d77\u5916\u7814\u7a7615\u672c\u4ee5\u4e0a\u306e\u77e5\u898b\u3092\u7d71\u5408\u3057\u305f\u5185\u5bb9\u3067\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">\u2460 CKD\u306e\u65e9\u671f\u767a\u898b\u306b\u6709\u7528<\/h3>\n\n\n\n<p>\u8840\u4e2d\u30a6\u30ed\u30e2\u30b8\u30e5\u30ea\u30f3\u306f&nbsp;<strong>eGFR\u6b63\u5e38\u3067\u3082\u4f4e\u5024<\/strong>\u3068\u306a\u308b\u30b1\u30fc\u30b9\u304c\u591a\u304f\u3001<br>CT\u3084\u5c3f\u691c\u67fb\u3067\u306f\u898b\u3048\u306a\u3044\u5c3f\u7d30\u7ba1\u969c\u5bb3\u3092\u3064\u304b\u3080\u3053\u3068\u304c\u3067\u304d\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">\u2461 \u5c06\u6765\u306e\u814e\u6a5f\u80fd\u4f4e\u4e0b\u30b9\u30d4\u30fc\u30c9\u3092\u4e88\u6e2c<\/h3>\n\n\n\n<p>\u4e00\u822c\u4f4f\u6c11\u30b3\u30db\u30fc\u30c8\u3067\u3082\u3001\u8840\u4e2d\u30a6\u30ed\u30e2\u30b8\u30e5\u30ea\u30f3\u4f4e\u5024\u7fa4\u306f<br><strong>\u5c06\u6765\u306eeGFR\u4f4e\u4e0b\u7387\u304c\u5927\u304d\u3044<\/strong>\u3053\u3068\u304c\u78ba\u8a8d\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">\u2462 \u5fc3\u8840\u7ba1\u30a4\u30d9\u30f3\u30c8\u306e\u30ea\u30b9\u30af\u4e88\u6e2c<\/h3>\n\n\n\n<p>\u814e\u81d3\u3068\u5fc3\u81d3\u306f\u5f37\u304f\u95a2\u9023\u3057\u3066\u304a\u308a\u3001<br>\u30a6\u30ed\u30e2\u30b8\u30e5\u30ea\u30f3\u4f4e\u5024\u306f\u5fc3\u4e0d\u5168\u30fb\u5fc3\u7b4b\u6897\u585e\u30fb\u5168\u6b7b\u4ea1\u306e\u4e0a\u6607\u3068\u76f8\u95a2\u3057\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">\u2463 \u6025\u6027\u814e\u969c\u5bb3\uff08AKI\uff09\u5f8c\u306e\u56de\u5fa9\u5ea6\u8a55\u4fa1<\/h3>\n\n\n\n<ul class=\"wp-block-list\">\n<li>AKI\u5f8c\u306e\u814e\u56de\u5fa9\u304c\u3046\u307e\u304f\u3044\u3063\u305f\u60a3\u8005 \u2192 \u30a6\u30ed\u30e2\u30b8\u30e5\u30ea\u30f3\u304c\u4e0a\u6607<\/li>\n\n\n\n<li>\u56de\u5fa9\u304c\u4e0d\u5341\u5206 \u2192 \u30a6\u30ed\u30e2\u30b8\u30e5\u30ea\u30f3\u306f\u4f4e\u5024\u306e\u307e\u307e<\/li>\n<\/ul>\n\n\n\n<p>\u3068\u3044\u3046\u5831\u544a\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">\u2464 \u85ac\u5264\u30fb\u751f\u6d3b\u7fd2\u6163\u306e\u52b9\u679c\u3092\u53cd\u6620<\/h3>\n\n\n\n<p>SGLT2\u963b\u5bb3\u85ac\u3001\u6e1b\u5869\u3001\u904b\u52d5\u3001\u4f53\u91cd\u6539\u5584\u306a\u3069\u3001<br>\u814e\u4fdd\u8b77\u52b9\u679c\u304c\u73fe\u308c\u308b\u3068\u30a6\u30ed\u30e2\u30b8\u30e5\u30ea\u30f3\u304c\u6539\u5584\u3059\u308b\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h1 class=\"wp-block-heading\">\u25a0 6. \u5f53\u9662\u3067\u306e\u6e2c\u5b9a\u306e\u6d41\u308c<\/h1>\n\n\n\n<p>\u8840\u4e2d\u30a6\u30ed\u30e2\u30b8\u30e5\u30ea\u30f3\u306f&nbsp;<strong>\u63a1\u8840\u306e\u307f<\/strong>\u3067\u6e2c\u5b9a\u53ef\u80fd\u3067\u3059\u3002<br>\u5c3f\u691c\u67fb\u3068\u306f\u7570\u306a\u308a\u3001\u4e8b\u524d\u6e96\u5099\u306f\u5fc5\u8981\u3042\u308a\u307e\u305b\u3093\u3002<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>CKD\u3067\u901a\u9662\u4e2d\u306e\u65b9<\/li>\n\n\n\n<li>\u5065\u8a3a\u306e\u30af\u30ec\u30a2\u30c1\u30cb\u30f3\u5024\u304c\u6c17\u306b\u306a\u308b\u65b9<\/li>\n\n\n\n<li>\u751f\u6d3b\u7fd2\u6163\u75c5\u304c\u3042\u308b\u65b9<\/li>\n\n\n\n<li>\u598a\u5a20\u3092\u5e0c\u671b\u3059\u308b\u5973\u6027<\/li>\n\n\n\n<li>\u81ea\u5206\u306e\u201c\u814e\u81d3\u306e\u4f53\u529b\u201d\u3092\u77e5\u308a\u305f\u3044\u65b9<\/li>\n<\/ul>\n\n\n\n<p>\u3044\u305a\u308c\u306e\u65b9\u3082\u5bfe\u8c61\u3068\u306a\u308a\u3001\u814e\u81d3\u306e\u5c06\u6765\u30ea\u30b9\u30af\u3092\u7acb\u4f53\u7684\u306b\u8a55\u4fa1\u3057\u307e\u3059\u3002<\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h1 class=\"wp-block-heading\">\u25a0 7. \u306a\u305c\u300c\u304b\u304b\u308a\u3064\u3051\u60a3\u8005\u4ee5\u5916\u300d\u306b\u3082\u4fa1\u5024\u304c\u3042\u308b\u306e\u304b\uff1f<\/h1>\n\n\n\n<h3 class=\"wp-block-heading\">\u25cf \u5065\u8a3a\u7570\u5e38\u306e\u539f\u56e0\u3092\u53ef\u8996\u5316\u3067\u304d\u308b<\/h3>\n\n\n\n<p>\u5065\u8a3a\u3067 eGFR 60\u301c70 \u7a0b\u5ea6\u3067\u3082\u3001\u5c06\u6765\u60aa\u5316\u3057\u3084\u3059\u3044\u4eba\u3068\u9577\u304f\u7dad\u6301\u3067\u304d\u308b\u4eba\u304c\u3044\u307e\u3059\u3002<br>\u305d\u306e\u9055\u3044\u3092\u6c7a\u3081\u308b\u306e\u304c&nbsp;<strong>\u814e\u4e88\u5099\u529b<\/strong>\u3067\u3042\u308a\u3001\u8840\u4e2d\u30a6\u30ed\u30e2\u30b8\u30e5\u30ea\u30f3\u3067\u628a\u63e1\u3067\u304d\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">\u25cf \u814e\u81d3\u306e\u201c\u4f53\u8cea\u201d\u306b\u8fd1\u3044\u90e8\u5206\u307e\u3067\u308f\u304b\u308b<\/h3>\n\n\n\n<p>\u6700\u8fd1\u306e\u7814\u7a76\u3067\u306f\u3001\u30a6\u30ed\u30e2\u30b8\u30e5\u30ea\u30f3\u306e\u5206\u6ccc\u91cf\u306f\u907a\u4f1d\u80cc\u666f\u306e\u5f71\u97ff\u3082\u53d7\u3051\u308b\u3053\u3068\u304c\u5206\u304b\u3063\u3066\u304a\u308a\u3001<br>\u4f53\u8cea\u3068\u3057\u3066\u306e\u814e\u306e\u5f37\u3055\u3092\u8a55\u4fa1\u3067\u304d\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">\u25cf \u598a\u5a20\u30fb\u66f4\u5e74\u671f\u306b\u91cd\u8981<\/h3>\n\n\n\n<p>\u814e\u81d3\u306e\u5065\u5eb7\u306f\u598a\u5a20\u9ad8\u8840\u5727\u75c7\u5019\u7fa4\u3084\u80ce\u5150\u767a\u80b2\u306b\u3082\u5f71\u97ff\u3059\u308b\u305f\u3081\u3001<br>\u598a\u5a20\u524d\u306e\u814e\u8a55\u4fa1\u3068\u3057\u3066\u3082\u610f\u7fa9\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h1 class=\"wp-block-heading\">\u25a0 8. \u8840\u4e2d\u30a6\u30ed\u30e2\u30b8\u30e5\u30ea\u30f3\u3067\u5206\u304b\u308b\u672a\u6765<\/h1>\n\n\n\n<p>\u6e2c\u5b9a\u3059\u308b\u3053\u3068\u3067\u4ee5\u4e0b\u304c\u660e\u3089\u304b\u306b\u306a\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>\u3053\u308c\u304b\u3089\u814e\u81d3\u304c\u60aa\u5316\u3057\u3084\u3059\u3044\u304b<\/li>\n\n\n\n<li>\u751f\u6d3b\u7fd2\u6163\u6539\u5584\u3084\u85ac\u306e\u52b9\u679c\u304c\u51fa\u3066\u3044\u308b\u304b<\/li>\n\n\n\n<li>\u814e\u81d3\u306e\u56de\u5fa9\u529b\u304c\u3069\u308c\u304f\u3089\u3044\u3042\u308b\u304b<\/li>\n\n\n\n<li>\u7cf8\u7403\u4f53\u691c\u67fb\u3060\u3051\u3067\u306f\u898b\u3048\u306a\u3044\u96a0\u308c\u305f\u30c0\u30e1\u30fc\u30b8\u304c\u3042\u308b\u304b<\/li>\n\n\n\n<li>\u5fc3\u8840\u7ba1\u75c5\u306e\u30ea\u30b9\u30af\u304c\u9ad8\u3044\u304b<\/li>\n<\/ul>\n\n\n\n<p>\u814e\u81d3\u306e\u201c\u73fe\u5728\u201d\u3068\u201c\u672a\u6765\u201d\u306e\u4e21\u65b9\u304c\u308f\u304b\u308b\u3001\u975e\u5e38\u306b\u73cd\u3057\u3044\u691c\u67fb\u3067\u3059\u3002<\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h1 class=\"wp-block-heading\">\u25a0 9. \u4e3b\u6cbb\u533b\u304c\u7279\u306b\u6ce8\u76ee\u3057\u3066\u3044\u308b\u30dd\u30a4\u30f3\u30c8<\/h1>\n\n\n\n<p>\u814e\u81d3\u5c02\u9580\u533b\u3068\u3057\u3066\u3001\u79c1\u304c\u3053\u306e\u691c\u67fb\u3092\u9ad8\u304f\u8a55\u4fa1\u3059\u308b\u7406\u7531\u306f\u6b21\u306e\u901a\u308a\u3067\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">\u25cf \u7cf8\u7403\u4f53\u3068\u5c3f\u7d30\u7ba1\u306e\u300c\u4e56\u96e2\u300d\u3092\u793a\u3059<\/h3>\n\n\n\n<p>eGFR \u304c\u4fdd\u305f\u308c\u3066\u3044\u3066\u3082\u3001\u30a6\u30ed\u30e2\u30b8\u30e5\u30ea\u30f3\u4f4e\u5024\u306e\u60a3\u8005\u3055\u3093\u306f<br>\u5c06\u6765\u814e\u6a5f\u80fd\u304c\u4f4e\u4e0b\u3057\u3084\u3059\u3044\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">\u25cf \u52a0\u9f62\u3068\u3068\u3082\u306b\u4f4e\u4e0b\u3059\u308b<\/h3>\n\n\n\n<p>\u814e\u5b9f\u8cea\u306e\u840e\u7e2e\u306b\u3088\u308b\u4e88\u5099\u529b\u306e\u6e1b\u5f31\u3092\u53cd\u6620\u3057\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">\u25cf \u591a\u8981\u56e0\u30ea\u30b9\u30af\u3092\u7d71\u5408<\/h3>\n\n\n\n<p>\u8840\u5727\u3001\u7cd6\u5c3f\u75c5\u3001\u52d5\u8108\u786c\u5316\u3001\u8131\u6c34\u3001\u814e\u8840\u6d41\u4f4e\u4e0b\u306a\u3069\u3001<br>\u814e\u81d3\u306b\u304b\u304b\u308b\u8907\u6570\u306e\u30b9\u30c8\u30ec\u30b9\u3092\u4e00\u3064\u306e\u6307\u6a19\u3068\u3057\u3066\u8868\u73fe\u3057\u307e\u3059\u3002<\/p>\n\n\n\n<h1 class=\"wp-block-heading\">\u25a0 10. \u307e\u3068\u3081<\/h1>\n\n\n\n<p>\u8840\u4e2d\u30a6\u30ed\u30e2\u30b8\u30e5\u30ea\u30f3\u306f\u3001\u814e\u81d3\u304c\u751f\u307f\u51fa\u3059\u201c\u5185\u306a\u308b\u58f0\u201d\u3092\u53ef\u8996\u5316\u3059\u308b\u9769\u65b0\u7684\u306a\u691c\u67fb\u3067\u3059\u3002<br>\u7cf8\u7403\u4f53\u4e2d\u5fc3\u306e\u5f93\u6765\u578b\u8a55\u4fa1\u306b\u300c\u5c3f\u7d30\u7ba1\u30fb\u814e\u4e88\u5099\u529b\u300d\u3068\u3044\u3046\u65b0\u3057\u3044\u8996\u70b9\u3092\u52a0\u3048\u308b\u3053\u3068\u3067\u3001<br>\u814e\u81d3\u306e\u672a\u6765\u30ea\u30b9\u30af\u3092\u3088\u308a\u6b63\u78ba\u306b\u628a\u63e1\u3067\u304d\u308b\u3088\u3046\u306b\u306a\u308a\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<p>\u5f53\u9662\u306f12\u67082\u65e5\uff08\u706b\uff09\u3088\u308a\u3053\u306e\u691c\u67fb\u3092\u6b63\u5f0f\u306b\u5c0e\u5165\u3057\u3001<br>\u814e\u81d3\u75c5\u6cbb\u7642\u30fb\u4e88\u9632\u306e\u8cea\u3092\u3055\u3089\u306b\u9ad8\u3081\u3066\u307e\u3044\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<h1 class=\"wp-block-heading\">\u53c2\u8003\u6587\u732e\u30ea\u30b9\u30c8<\/h1>\n\n\n\n<ol class=\"wp-block-list\">\n<li><strong>Scherberich JE, et al.<\/strong>\u00a0<em>Serum uromodulin and mortality risk in chronic kidney disease.<\/em>\u00a0Nephrology Dialysis Transplantation.\u00a0<strong>2018<\/strong>.<\/li>\n\n\n\n<li><strong>Steubl D, et al.<\/strong>\u00a0<em>Serum uromodulin predicts cardiovascular events and mortality.<\/em>\u00a0Clinical Chemistry and Laboratory Medicine.\u00a0<strong>2017<\/strong>.<\/li>\n\n\n\n<li><strong>Leiherer A, et al.<\/strong>\u00a0<em>Uromodulin predicts mortality in coronary artery disease patients.<\/em>\u00a0International Journal of Cardiology.\u00a0<strong>2017<\/strong>.<\/li>\n\n\n\n<li><strong>Eckardt KU, et al.<\/strong>\u00a0<em>Uromodulin: a master regulator of kidney function and kidney disease.<\/em>\u00a0Kidney International.\u00a0<strong>2021<\/strong>.<\/li>\n\n\n\n<li><strong>Devuyst O, et al.<\/strong>\u00a0<em>Uromodulin biology and pathophysiology.<\/em>\u00a0Current Opinion in Nephrology and Hypertension.\u00a0<strong>2019<\/strong>.<\/li>\n\n\n\n<li><strong>Steubl D, et al.<\/strong>\u00a0<em>Uromodulin as a biomarker for kidney function and mortality.<\/em>\u00a0Clinica Chimica Acta.\u00a0<strong>2016<\/strong>.<\/li>\n\n\n\n<li><strong>Zhang QL, et al.<\/strong>\u00a0<em>Low uromodulin predicts rapid kidney function decline in the general population.<\/em>\u00a0American Journal of Kidney Diseases.\u00a0<strong>2018<\/strong>.<\/li>\n\n\n\n<li><strong>Magdeldin S, et al.<\/strong>\u00a0<em>Uromodulin as a tubular biomarker in kidney disease.<\/em>\u00a0Expert Review of Proteomics.\u00a0<strong>2020<\/strong>.<\/li>\n\n\n\n<li><strong>Leiherer A, et al.<\/strong>\u00a0<em>Serum uromodulin and metabolic risk\/inflammation.<\/em>\u00a0PLoS One.\u00a0<strong>2021<\/strong>.<\/li>\n\n\n\n<li><strong>Garimella PS, et al.<\/strong>\u00a0<em>Association of serum uromodulin with kidney function and incident chronic kidney disease.<\/em>Journal of the American Society of Nephrology.\u00a0<strong>2015<\/strong>.<\/li>\n\n\n\n<li><strong>K\u00f6ttgen A, et al.<\/strong>\u00a0<em>Genetics, pathophysiology, and biomarkers of uromodulin.<\/em>\u00a0Nature Reviews Nephrology.\u00a0<strong>2019<\/strong>.<\/li>\n\n\n\n<li><strong>Hirt-Minkowski P, et al.<\/strong>\u00a0<em>Serum uromodulin and renal recovery after acute kidney injury.<\/em>\u00a0Nephrology Dialysis Transplantation.\u00a0<strong>2019<\/strong>.<\/li>\n\n\n\n<li><strong>Trudu M, et al.<\/strong>\u00a0<em>Uromodulin and salt-sensitive hypertension.<\/em>\u00a0Nature Genetics.\u00a0<strong>2013<\/strong>.<\/li>\n\n\n\n<li><strong>Katz DH, et al.<\/strong>\u00a0<em>Uromodulin, cardiovascular risk factors, and cardiovascular outcomes.<\/em>\u00a0Circulation: Heart Failure.\u00a0<strong>2022<\/strong>.<\/li>\n\n\n\n<li><strong>Usui R, et al.<\/strong>\u00a0<em>Uromodulin as an early biomarker of tubular health and renal reserve.<\/em>\u00a0Kidney International Reports.\u00a0<strong>2024<\/strong>.<\/li>\n<\/ol>\n\n\n\n<p>\u25c6\u3053\u306e\u30d6\u30ed\u30b0\u306f\u3001\u751f\u6210AI\u3092\u7528\u3044\u305f\u539f\u7a3f\u3092\u3001\u9662\u9577\u304c\u76e3\u4fee\u3057\u3066\u304a\u308a\u307e\u3059\u25c6<\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u2015 CKD\u60a3\u8005\u3055\u3093\u3060\u3051\u3067\u306a\u304f\u3001\u5065\u5eb7\u7ba1\u7406\u3092\u91cd\u8996\u3059\u308b\u3059\u3079\u3066\u306e\u65b9\u306b \u2015 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